What Next: TBD | Tech, power, and the future

Last May, a 12-year-old with sickle cell anemia was the first person to receive a new gene therapy to treat the disease. The process is painful, expensive, and still frightening and uncertain, but biomedical researchers are cautiously calling it a “cure.” Guests: Gina Kolata, medical reporter for the New York Times Deb and Keith Cromer, parents to Kendric Cromer, the first person in the world to go through a commercially approved gene therapy for sickle cell anemia. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Evan Campbell, Patrick Fort, and Cheyna Roth. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Department of Justice has released its recommendations for how Google’s monopoly on web search should be broken up. Top of their wishlist? Spinning off their web browser Chrome.  But with a new administration coming to the White House, will Google have to comply? Guest: Leah Nylen, antitrust reporter for Bloomberg News Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Learn more about your ad choices. Visit megaphone.fm/adchoices

Since Elon Musk took over, Twitter—er, sorry “X”—has been slowly deflating. But given that soon you’ll be getting yelled at by right-wing trolls directly from White House press briefings, and your data is being swept up to train A.I., is there any reason to stay on the site at all anymore?  Guest: Nitish Pahwa, Slate business writer. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Evan Campbell, Patrick Fort, and Alyssa Jeong Perry. Learn more about your ad choices. Visit megaphone.fm/adchoices

Going on Joe Rogan’s podcast didn’t fit into Kamala Harris’s last month of campaigning, which consisted of a careful diet of traditional media and specifically selected appearances. It came up short against Donald Trump’s “get on mic with that guy and his big following” strategy.  Guest: Makena Kelly, senior writer at Wired. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Many folks were surprised at how soundly Donald Trump defeated Kamala Harris in the election, especially since they thought the polls made it seem like a coin flip. The problem is, that’s not quite what the polls were saying. Guest: Tatishe M. Nteta, Provost Professor of Political Science, Director of UMass Poll Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

As Elon Musk channeled his considerable resources towards Donald Trump’s campaign, there was talk about what his role in the new Trump administration would be. If his stint leading Twitter is any indication, the federal government could be in for a bumpy ride. Guest: Zoë Schiffer, incoming director of business and industry at Wired, author of Extremely Hardcore: Inside Elon Musk’s Twitter. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Voters in swing states are being subjected to constant political messages—on billboards, commercials and, increasingly, via text messages. But are dozens of “make a plan to vote” texts you’re receiving going to make a difference? Guest: Jacob Neiheisel, political science professor at the University at Buffalo  Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Learn more about your ad choices. Visit megaphone.fm/adchoices

How did Elon Musk go from a poster to someone pumping millions of dollars towards Donald Trump? And what’s he hoping to get for doing so? Guest: Max Chafkin, Bloomberg Businessweek columnist.  Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

He didn’t find his grandfather. But traveling to, photographing, and uploading his grandfather’s memorial stone gave him something else.  Guest: Tony Tran, senior tech editor at Slate and author of the feature “My Weekends with the Dead.” Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

This election cycle, TikTok has evolved into a news-and-politics delivery mechanism. Will it make a difference? Guest: Sapna Maheshwari, reporting on TikTok and other tech for the New York Times. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Learn more about your ad choices. Visit megaphone.fm/adchoices

America’s head of cybersecurity isn’t worried about the election being hacked or the results being tampered with. But this election cycle does have her worried for our democracy. Guest: Jen Easterly, Director of Cybersecurity and Infrastructure Security Agency  Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Elon Musk went from voting for Hillary to supporting Trump so hard that he may have broken election laws. And with Musk influencing both on X and in campaign finance, Democrats are kicking themselves for letting him go. What will his political and financial support actually amount to this election season?  Guest: Teddy Schleifer, New York Times reporter covering campaign finance and billionaire influence on American politics. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Evan Campbell, Patrick Fort, and Cheyna Roth. Learn more about your ad choices. Visit megaphone.fm/adchoices

How did 23andMe go from the peak of the double-helix to a death spiral? And if it goes under, is all of the genetic data it collected at risk?  Guest: Kristen V. Brown, staff writer covering health for The Atlantic. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Evan Campbell, Patrick Fort, and Cheyna Roth. Learn more about your ad choices. Visit megaphone.fm/adchoices

The crypto project “World Liberty Financial,” which was announced on X by Donald Trump, isn’t a cryptocurrency, nor a crypto-exchange, nor is it actually run by any Trumps. The truth is even stranger.  Guest: David Yaffe-Bellany, New York Times reporter Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Decades ago, Three Mile Island was shut down after a near catastrophic nuclear meltdown. So why is Microsoft paying over a billion dollars to open it back up?  Guest: Matt Reynolds, senior writer at Wired Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Learn more about your ad choices. Visit megaphone.fm/adchoices

In the aftermath of Hurricane Helene, the idea of a climate haven has been upended. And as the climate change gets worse every year, fewer places will be safe from its devastation. Guest: Sarah Kaplan, Washington Post climate reporter covering humanity's response to a warming world. Keith Campbell, managing editor at the Asheville Watchdog Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

America is caught in a vicious cycle of trying to alleviate traffic by expanding and building more highways, only for them to clog right up with more cars. How do you beat the traffic? Guest: David Zipper, Senior Fellow at the MIT Mobility Initiative who writes about transportation policy. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Public.com+Public Investing: All investing involves risk. Brokerage services for US listed securities, options and bonds in a self-directed brokerage account are offered by Public Investing, member FINRA & SIPC. Not investment advice. Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank.Cryptocurrency trading services are offered by Bakkt Crypto Solutions, LLC (NMLS ID 1828849), which is licensed to engage in virtual currency business activity by the NYSDFS. Cryptocurrency is highly speculative, involves a high degree of risk, and has the potential for loss of the entire amount of an investment. Cryptocurrency holdings are not protected by the FDIC or SIPC. . See public.com/#disclosures-main for more information. Learn more about your ad choices. Visit megaphone.fm/adchoices

Over the last decade, the European Union has been the vanguard regulating Big Tech, and the push has been led by Margrethe Vestager. As she steps down, Vestager is looking both back at the battles she’s fought, and how the fight will continue.  Guest: Margrethe Vestager, European Commissioner for Competition. the European Commission’s Executive Vice President on a Europe Fit for the Digital Age. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Given Laura Loomer’s history of saying outright offensive and often bewildering things, how did she get into the Trump campaign’s inner circle?   Guest: Ken Bensinger, New York Times politics reporter. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Learn more about your ad choices. Visit megaphone.fm/adchoices

Instagram’s new default privacy settings for teenagers are designed to keep kids safe from strangers online. It’s a worthy endeavor, but are privacy settings enough? And what about all the other hazards teenagers face on social media?   Guest: Natasha Singer, New York Times tech reporter, focused on how technology is affecting childhood and schooling. Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Podcast production by Evan Campbell, Patrick Fort, and Cheyna Roth. Public.com+Public Investing Disclosure: Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank. See public.com/#disclosures-main for more information. Learn more about your ad choices. Visit megaphone.fm/adchoices